Learning how our world works and about its interconnectedness are the backbone of our Middle School science program. Students explore these concepts by engaging in activities from a variety of fields: life sciences, physical science, and earth science. Experimental investigations, inquiries, demonstrations, discussions, and group and independent projects help students construct their understanding. Guiding questions we call “throughlines” focus the curriculum and encourage students, as they practice the scientific process, to apply what they are learning to the great issues of our time, such as habitat loss, diminishing biodiversity, food security, and climate change. Special attention is given to the lessons we can learn from our extraordinary LEED platinum Middle School building, which encourages us to consider how we can “let our lives speak,” applying our scientific understanding to make the world a better place.